Molecular Playground/IntegrinBeta1: Difference between revisions
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==Studying integrin-mediated metastasis ''in vitro''== | |||
<Structure load='3VI4' size='350' frame='true' align='right' caption='Integrin Beta 1 Alpha 5' scene='60/609772/Integrinb1alpha5/1' /> | <Structure load='3VI4' size='350' frame='true' align='right' caption='Integrin Beta 1 Alpha 5' scene='60/609772/Integrinb1alpha5/1' /> | ||
==Structure== | ==Structure== | ||
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==Peyton Lab Research Interests== | ==Peyton Lab Research Interests== | ||
The [http://www.peytonlab.org/ Peyton lab] studies how cells process chemical and physical cues from the extracellular matrix and how these interactions play a role in the progression of cardiovascular disease and cancer. We aim to understand the downstream signaling pathways activated when cells use their integrins to bind to matrix and how this translates to the disease of interest. | The [http://www.peytonlab.org/ Peyton lab] studies how cells process chemical and physical cues from the extracellular matrix and how these interactions play a role in the progression of cardiovascular disease and cancer. We aim to understand the downstream signaling pathways activated when cells use their integrins to bind to matrix and how this translates to the disease of interest. | ||
</StructureSection> | |||
==References== | ==References== | ||
[1] C. Saravanan, F. Liu, I.K. Gipson and N. Panjwani1. Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on 31 integrin. Journal of Cell Science 122, 3684-3693 Published by The Company of Biologists (2009). doi:10.1242/jcs.045674. | [1] C. Saravanan, F. Liu, I.K. Gipson and N. Panjwani1. Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on 31 integrin. Journal of Cell Science 122, 3684-3693 Published by The Company of Biologists (2009). doi:10.1242/jcs.045674. | ||
