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| <scene name='60/607850/Lysin_fertilization_protein/1'>push here to see Lysine structure</scene>
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| == Function == | | == Function == |
Revision as of 07:47, 24 November 2014
egg lysin
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Function
Egg Lysin, a protein from abalone sperm, creates a hole in the envelope of the egg, permitting the sperm to pass through the envelope and fuse with the egg.
Relevance
Structural highlights
The structure of lysin, refined at 1.9 angstroms resolution, reveals an alpha-helical, amphipathic moleculeTo see alpha helixes press here. you can see the alpha helixes in pink. the surface of the protein exhibits three features: two tracks of basic residues that span the length of the molecule, a solvent-exposed cluster of aromatic and aliphatic amino acids,(in green) and an extended amino-terminal hypervariable domain that is species-specific. The structure suggests possible mechanisms of action.
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References
The crystal structure of lysin, a fertilization protein.
Shaw A1, McRee DE, Vacquier VD, Stout CD.
