Gp41: Difference between revisions
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{{STRUCTURE_1aik| PDB=1aik | SIZE=400| SCENE= |right|CAPTION=Gp41 N chain (magenta) and C chain (pink) with acetylated ends, [[1aik]]. }} | {{STRUCTURE_1aik| PDB=1aik | SIZE=400| SCENE= |right|CAPTION=Gp41 N chain (magenta) and C chain (pink) with acetylated ends, [[1aik]]. }} | ||
== Function == | |||
'''Gp41''' is a subunit of the envelope protein of retrovirus<ref>PMID:9630213</ref>. Gp41 is a transmembrane protein and contains several sites which are involved in the infection of the host cells. Gp160 is the cleavable precursor of Gp41 and Gp120. For more details see [[Hiv env proteins]]. | |||
== Relevance == | |||
Fusion inhibitory drugs which bind to Gp41 prevent the attachment of the ~HIV-1 virus to the cell<ref>PMID:15180542</ref>. | |||
== 3D Structures of Gp41 == | == 3D Structures of Gp41 == | ||
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**[[1qbz]], [[1jq0]] – Gp41 core (mutant)<br /> | **[[1qbz]], [[1jq0]] – Gp41 core (mutant)<br /> | ||
}} | }} | ||
== References == | |||
<references/> | |||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
