1m75: Difference between revisions

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|PDB= 1m75 |SIZE=350|CAPTION= <scene name='initialview01'>1m75</scene>, resolution 2.30&Aring;
|PDB= 1m75 |SIZE=350|CAPTION= <scene name='initialview01'>1m75</scene>, resolution 2.30&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=CAA:ACETOACETYL-COENZYME+A'>CAA</scene> and <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
|LIGAND= <scene name='pdbligand=CAA:ACETOACETYL-COENZYME+A'>CAA</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/3-hydroxyacyl-CoA_dehydrogenase 3-hydroxyacyl-CoA dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.35 1.1.1.35]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxyacyl-CoA_dehydrogenase 3-hydroxyacyl-CoA dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.35 1.1.1.35] </span>
|GENE= HCDH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= HCDH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[1f0y|1F0Y]], [[1m76|1m76]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m75 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m75 OCA], [http://www.ebi.ac.uk/pdbsum/1m75 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1m75 RCSB]</span>
}}
}}


'''Crystal Structure of the N208S Mutant of L-3-Hydroxyacyl-COA Dehydrogenase in Complex with NAD and Acetoacetyl-COA'''
'''Crystal Structure of the N208S Mutant of L-3-Hydroxyacyl-COA Dehydrogenase in Complex with NAD and Acetoacetyl-COA'''


==Disease==
Known diseases associated with this structure: 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=300256 300256]], 3-hydroxyacyl-CoA dehydrogenase deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601609 601609]], Hyperinsulinemic hypoglycemia, familial, 4 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=601609 601609]]


==About this Structure==
==About this Structure==
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[[Category: Banaszak, L J.]]
[[Category: Banaszak, L J.]]
[[Category: Barycki, J J.]]
[[Category: Barycki, J J.]]
[[Category: CAA]]
[[Category: NAD]]
[[Category: dehydrogenase]]
[[Category: dehydrogenase]]
[[Category: rossmann fold]]
[[Category: rossmann fold]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:39:46 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 22:12:14 2008''

Revision as of 19:12, 30 March 2008

File:1m75.gif


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1m75, resolution 2.30Å
Ligands: CAA, NAD
Gene: HCDH (Homo sapiens)
Activity: 3-hydroxyacyl-CoA dehydrogenase, with EC number 1.1.1.35
Related: 1F0Y, 1m76


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal Structure of the N208S Mutant of L-3-Hydroxyacyl-COA Dehydrogenase in Complex with NAD and Acetoacetyl-COA


About this Structure

1M75 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Sun Mar 30 22:12:14 2008

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