1okz: Difference between revisions

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|PDB= 1okz |SIZE=350|CAPTION= <scene name='initialview01'>1okz</scene>, resolution 2.51&Aring;
|PDB= 1okz |SIZE=350|CAPTION= <scene name='initialview01'>1okz</scene>, resolution 2.51&Aring;
|SITE= <scene name='pdbsite=BC3:Ucn+Binding+Site+For+Chain+A'>BC3</scene>
|SITE= <scene name='pdbsite=BC3:Ucn+Binding+Site+For+Chain+A'>BC3</scene>
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UCN:7-HYDROXYSTAUROSPORINE'>UCN</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|LIGAND= <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UCN:7-HYDROXYSTAUROSPORINE'>UCN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferred_entry:_2.7.11.1 Transferred entry: 2.7.11.1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.37 2.7.1.37]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span>
|GENE=  
|GENE=  
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1okz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1okz OCA], [http://www.ebi.ac.uk/pdbsum/1okz PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1okz RCSB]</span>
}}
}}


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Structural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibition., Komander D, Kular GS, Bain J, Elliott M, Alessi DR, Van Aalten DM, Biochem J. 2003 Oct 15;375(Pt 2):255-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12892559 12892559]
Structural basis for UCN-01 (7-hydroxystaurosporine) specificity and PDK1 (3-phosphoinositide-dependent protein kinase-1) inhibition., Komander D, Kular GS, Bain J, Elliott M, Alessi DR, Van Aalten DM, Biochem J. 2003 Oct 15;375(Pt 2):255-62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12892559 12892559]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Transferred entry: 2 7.11 1]]
[[Category: Aalten, D M.F Van.]]
[[Category: Aalten, D M.F Van.]]
[[Category: Alessi, D R.]]
[[Category: Alessi, D R.]]
[[Category: Komander, D.]]
[[Category: Komander, D.]]
[[Category: Kular, G S.]]
[[Category: Kular, G S.]]
[[Category: GOL]]
[[Category: SO4]]
[[Category: UCN]]
[[Category: 7-hydroxy staurosporine]]
[[Category: 7-hydroxy staurosporine]]
[[Category: atp-binding]]
[[Category: atp-binding]]
Line 40: Line 40:
[[Category: ucn-01]]
[[Category: ucn-01]]


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