1os5: Difference between revisions

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|LIGAND= <scene name='pdbligand=NH1:3-(4-AMINO-2-TERT-BUTYL-5-METHYL-PHENYLSULFANYL)-6-CYCLOPENTYL-4-HYDROXY-6-[2-(4-HYDROXY-PHENYL)-ETHYL]-5,6-DIHYDRO-PYRAN-2-ONE'>NH1</scene>
|LIGAND= <scene name='pdbligand=NH1:3-(4-AMINO-2-TERT-BUTYL-5-METHYL-PHENYLSULFANYL)-6-CYCLOPENTYL-4-HYDROXY-6-[2-(4-HYDROXY-PHENYL)-ETHYL]-5,6-DIHYDRO-PYRAN-2-ONE'>NH1</scene>
|ACTIVITY=  
|ACTIVITY=  
|GENE= NS5B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=42791 Hepatitis C virus subtype 3b])
|GENE= NS5B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31647 Hepatitis C virus subtype 1b])
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1os5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1os5 OCA], [http://www.ebi.ac.uk/pdbsum/1os5 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1os5 RCSB]</span>
}}
}}


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==About this Structure==
==About this Structure==
1OS5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_3b Hepatitis c virus subtype 3b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OS5 OCA].  
1OS5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1b Hepatitis c virus subtype 1b]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OS5 OCA].  


==Reference==
==Reference==
Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme., Love RA, Parge HE, Yu X, Hickey MJ, Diehl W, Gao J, Wriggers H, Ekker A, Wang L, Thomson JA, Dragovich PS, Fuhrman SA, J Virol. 2003 Jul;77(13):7575-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12805457 12805457]
Crystallographic identification of a noncompetitive inhibitor binding site on the hepatitis C virus NS5B RNA polymerase enzyme., Love RA, Parge HE, Yu X, Hickey MJ, Diehl W, Gao J, Wriggers H, Ekker A, Wang L, Thomson JA, Dragovich PS, Fuhrman SA, J Virol. 2003 Jul;77(13):7575-81. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12805457 12805457]
[[Category: Hepatitis c virus subtype 3b]]
[[Category: Hepatitis c virus subtype 1b]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Diehl, W.]]
[[Category: Diehl, W.]]
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[[Category: Wriggers, H.]]
[[Category: Wriggers, H.]]
[[Category: Yu, X.]]
[[Category: Yu, X.]]
[[Category: NH1]]
[[Category: enzyme-inhibitor complex]]
[[Category: enzyme-inhibitor complex]]


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