4ab1: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ab1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ab1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ab1 RCSB], [http://www.ebi.ac.uk/pdbsum/4ab1 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ab1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ab1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ab1 RCSB], [http://www.ebi.ac.uk/pdbsum/4ab1 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/EST1_HUMAN EST1_HUMAN]] Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate.<ref>PMID:7980644</ref> <ref>PMID:9169443</ref> | |||
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== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
