2yem: Difference between revisions
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==Crystal Structure of the Second Bromodomain of Human Brd4 with the inhibitor GW841819X== | ==Crystal Structure of the Second Bromodomain of Human Brd4 with the inhibitor GW841819X== | ||
<StructureSection load='2yem' size='340' side='right' caption='[[2yem]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='2yem' size='340' side='right' caption='[[2yem]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2yem]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2yem]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YEM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YEM FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=WSH:BENZYL+[(4R)-1-METHYL-6-PHENYL-4H-[1,2,4]TRIAZOLO[4,3-A][1,4]BENZODIAZEPIN-4-YL]CARBAMATE'>WSH</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=WSH:BENZYL+[(4R)-1-METHYL-6-PHENYL-4H-[1,2,4]TRIAZOLO[4,3-A][1,4]BENZODIAZEPIN-4-YL]CARBAMATE'>WSH</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yel|2yel]], [[2yek|2yek]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yel|2yel]], [[2yek|2yek]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yem OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2yem RCSB], [http://www.ebi.ac.uk/pdbsum/2yem PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yem OCA], [http://pdbe.org/2yem PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yem RCSB], [http://www.ebi.ac.uk/pdbsum/2yem PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yem ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 2yem" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Bromodomain-containing protein|Bromodomain-containing protein]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Human]] | ||
[[Category: Chung, C W]] | [[Category: Chung, C W]] | ||
[[Category: Epigenetic reader]] | [[Category: Epigenetic reader]] | ||
[[Category: Histone]] | [[Category: Histone]] | ||
[[Category: Signaling protein]] | [[Category: Signaling protein]] | ||
