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==CRYSTAL STRUCTURE OF CHECKPOINT KINASE 2 IN COMPLEX WITH INHIBITOR PV1531==
==CRYSTAL STRUCTURE OF CHECKPOINT KINASE 2 IN COMPLEX WITH INHIBITOR PV1531==
<StructureSection load='2ycf' size='340' side='right' caption='[[2ycf]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
<StructureSection load='2ycf' size='340' side='right' caption='[[2ycf]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ycf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YCF FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ycf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YCF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=YCF:(2E)-N-HYDROXY-2-[1-(4-{[(4-{(1E)-1-[2-(N-HYDROXYCARBAMIMIDOYL)HYDRAZINYLIDENE]ETHYL}PHENYL)CARBAMOYL]AMINO}PHENYL)ETHYLIDENE]HYDRAZINECARBOXIMIDAMIDE'>YCF</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=YCF:(2E)-N-HYDROXY-2-[1-(4-{[(4-{(1E)-1-[2-(N-HYDROXYCARBAMIMIDOYL)HYDRAZINYLIDENE]ETHYL}PHENYL)CARBAMOYL]AMINO}PHENYL)ETHYLIDENE]HYDRAZINECARBOXIMIDAMIDE'>YCF</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wti|2wti]], [[2xbj|2xbj]], [[2cn8|2cn8]], [[2w0j|2w0j]], [[2wtc|2wtc]], [[2wtj|2wtj]], [[2xm9|2xm9]], [[2w7x|2w7x]], [[1gxc|1gxc]], [[2cn5|2cn5]], [[2xm8|2xm8]], [[2wtd|2wtd]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wti|2wti]], [[2xbj|2xbj]], [[2cn8|2cn8]], [[2w0j|2w0j]], [[2wtc|2wtc]], [[2wtj|2wtj]], [[2xm9|2xm9]], [[2w7x|2w7x]], [[1gxc|1gxc]], [[2cn5|2cn5]], [[2xm8|2xm8]], [[2wtd|2wtd]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ycf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ycf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ycf RCSB], [http://www.ebi.ac.uk/pdbsum/2ycf PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ycf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ycf OCA], [http://pdbe.org/2ycf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ycf RCSB], [http://www.ebi.ac.uk/pdbsum/2ycf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2ycf ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2ycf" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Jobson, A G]]
[[Category: Jobson, A G]]
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