1rlb: Difference between revisions
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|PDB= 1rlb |SIZE=350|CAPTION= <scene name='initialview01'>1rlb</scene>, resolution 3.1Å | |PDB= 1rlb |SIZE=350|CAPTION= <scene name='initialview01'>1rlb</scene>, resolution 3.1Å | ||
|SITE= | |SITE= | ||
|LIGAND= <scene name='pdbligand=REA:RETINOIC ACID'>REA</scene> | |LIGAND= <scene name='pdbligand=REA:RETINOIC+ACID'>REA</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rlb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rlb OCA], [http://www.ebi.ac.uk/pdbsum/1rlb PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rlb RCSB]</span> | |||
}} | }} | ||
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==Overview== | ==Overview== | ||
The three-dimensional structure of the complex formed by two plasma proteins, transthyretin and retinol-binding protein, was determined from x-ray diffraction data to a nominal resolution of 3.1 angstroms. One tetramer of transthyretin was bound to two molecules of retinol-binding protein. The two retinol-binding protein molecules established molecular interactions with the same transthyretin dimer, and each also made contacts with one of the other two monomers. Thus, the other two potential binding sites in a transthyretin tetramer were blocked. The amino acid residues of the retinol-binding protein that were involved in the contacts were close to the retinol-binding site. | The three-dimensional structure of the complex formed by two plasma proteins, transthyretin and retinol-binding protein, was determined from x-ray diffraction data to a nominal resolution of 3.1 angstroms. One tetramer of transthyretin was bound to two molecules of retinol-binding protein. The two retinol-binding protein molecules established molecular interactions with the same transthyretin dimer, and each also made contacts with one of the other two monomers. Thus, the other two potential binding sites in a transthyretin tetramer were blocked. The amino acid residues of the retinol-binding protein that were involved in the contacts were close to the retinol-binding site. | ||
==About this Structure== | ==About this Structure== | ||
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[[Category: Monaco, H L.]] | [[Category: Monaco, H L.]] | ||
[[Category: Rizzi, M.]] | [[Category: Rizzi, M.]] | ||
[[Category: complex (protein/protein)]] | [[Category: complex (protein/protein)]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:29:44 2008'' | ||
