4dl1: Difference between revisions
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{{Large structure}} | |||
==Crystal Structure of human Myeloperoxidase with covalent thioxanthine analog== | ==Crystal Structure of human Myeloperoxidase with covalent thioxanthine analog== | ||
<StructureSection load='4dl1' size='340' side='right' caption='[[4dl1]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='4dl1' size='340' side='right' caption='[[4dl1]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Myeloperoxidase Myeloperoxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.2.2 1.11.2.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Myeloperoxidase Myeloperoxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.2.2 1.11.2.2] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dl1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4dl1 RCSB], [http://www.ebi.ac.uk/pdbsum/4dl1 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4dl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dl1 OCA], [http://pdbe.org/4dl1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4dl1 RCSB], [http://www.ebi.ac.uk/pdbsum/4dl1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4dl1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
{{Large structure}} | |||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/PERM_HUMAN PERM_HUMAN]] Defects in MPO are the cause of myeloperoxidase deficiency (MPOD) [MIM:[http://omim.org/entry/254600 254600]]. A disorder characterized by decreased myeloperoxidase activity in neutrophils and monocytes that results in disseminated candidiasis.<ref>PMID:8142659</ref> <ref>PMID:7904599</ref> <ref>PMID:8621627</ref> <ref>PMID:9637725</ref> <ref>PMID:9354683</ref> | [[http://www.uniprot.org/uniprot/PERM_HUMAN PERM_HUMAN]] Defects in MPO are the cause of myeloperoxidase deficiency (MPOD) [MIM:[http://omim.org/entry/254600 254600]]. A disorder characterized by decreased myeloperoxidase activity in neutrophils and monocytes that results in disseminated candidiasis.<ref>PMID:8142659</ref> <ref>PMID:7904599</ref> <ref>PMID:8621627</ref> <ref>PMID:9637725</ref> <ref>PMID:9354683</ref> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4dl1" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
*[[Myeloperoxidase|Myeloperoxidase]] | *[[Myeloperoxidase|Myeloperoxidase]] | ||
*[[Sandbox WWC11|Sandbox WWC11]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
