3zze: Difference between revisions
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==Crystal structure of C-MET kinase domain in complex with N'-((3Z)-4- chloro-7-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-2-(4- hydroxyphenyl)propanohydrazide== | ==Crystal structure of C-MET kinase domain in complex with N'-((3Z)-4- chloro-7-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-2-(4- hydroxyphenyl)propanohydrazide== | ||
<StructureSection load='3zze' size='340' side='right' caption='[[3zze]], [[Resolution|resolution]] 1.87Å' scene=''> | <StructureSection load='3zze' size='340' side='right' caption='[[3zze]], [[Resolution|resolution]] 1.87Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3zze]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3zze]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZZE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZZE FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6XP:(2S)-N-[(3R)-4-CHLORO-7-METHYL-2-OXO-2,3-DIHYDRO-1H-INDOL-3-YL]-2-(4-HYDROXYPHENYL)PROPANEHYDRAZIDE'>6XP</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=6XP:(2S)-N-[(3R)-4-CHLORO-7-METHYL-2-OXO-2,3-DIHYDRO-1H-INDOL-3-YL]-2-(4-HYDROXYPHENYL)PROPANEHYDRAZIDE'>6XP</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1r1w|1r1w]], [[1ux3|1ux3]], [[2wgj|2wgj]], [[1fyr|1fyr]], [[2wd1|2wd1]], [[2uzx|2uzx]], [[1shy|1shy]], [[2cew|2cew]], [[2wkm|2wkm]], [[2uzy|2uzy]], [[1r0p|1r0p]], [[2g15|2g15]], [[1ssl|1ssl]], [[3zxz|3zxz]], [[4aoi|4aoi]], [[4ap7|4ap7]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1r1w|1r1w]], [[1ux3|1ux3]], [[2wgj|2wgj]], [[1fyr|1fyr]], [[2wd1|2wd1]], [[2uzx|2uzx]], [[1shy|1shy]], [[2cew|2cew]], [[2wkm|2wkm]], [[2uzy|2uzy]], [[1r0p|1r0p]], [[2g15|2g15]], [[1ssl|1ssl]], [[3zxz|3zxz]], [[4aoi|4aoi]], [[4ap7|4ap7]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zze OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zze RCSB], [http://www.ebi.ac.uk/pdbsum/3zze PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zze FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zze OCA], [http://pdbe.org/3zze PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3zze RCSB], [http://www.ebi.ac.uk/pdbsum/3zze PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3zze ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Disease == | == Disease == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3zze" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Human]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Cui, J J]] | [[Category: Cui, J J]] | ||