4iop: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 7: | Line 7: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iop OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iop RCSB], [http://www.ebi.ac.uk/pdbsum/4iop PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iop OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iop RCSB], [http://www.ebi.ac.uk/pdbsum/4iop PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CLC2A_HUMAN CLC2A_HUMAN]] Plays a role in modulating the extent of T-cell expansion. Enhances the expansion of TCR-stimulated T-cells by increasing their survival through enhanced expression of anti-apoptotic proteins. May modulate the capacity of T-cells to home to lymph nodes through SELL. Facilitates dedicated immune recognition of keratinocytes via interaction with its receptor KLRF2 by stimulating natural killer cell mediated cytotoxicity.<ref>PMID:18550855</ref> <ref>PMID:20194751</ref> [[http://www.uniprot.org/uniprot/KLRF2_HUMAN KLRF2_HUMAN]] C-type lectin-like receptor involved in natural killer cell mediated cytotoxicity and cytokine secretion in keratinocytes via its interaction with CLEC2A. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
