Sandbox Reserved 958: Difference between revisions
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The '''N-terminal domain''' presents a HHCC motif which is a pseudo zinc-finger complexing with zinc ions. The zinc ejection impedes the 3'-processing process and pertubs the integrase multimerisation<ref name="Carayon">PMID:20164093</ref>. Therefore the presence of this ion is necessary the virus life cycle. | The '''N-terminal domain''' presents a HHCC motif which is a pseudo zinc-finger complexing with zinc ions. The zinc ejection impedes the 3'-processing process and pertubs the integrase multimerisation<ref name="Carayon">PMID:20164093</ref>. Therefore the presence of this ion is necessary the virus life cycle. | ||
The '''central domain''' | The '''central domain''' which corresponds to the catalytic domain contains the catalytic triad by association of two aspartates and one glutamate residues | ||
== DNA binding == | == DNA binding == | ||
