1cxo: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cxo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cxo RCSB], [http://www.ebi.ac.uk/pdbsum/1cxo PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1cxo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1cxo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1cxo RCSB], [http://www.ebi.ac.uk/pdbsum/1cxo PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/CX1_NAJPA CX1_NAJPA]] Basic protein that bind to cell membrane and depolarizes cardiomyocytes. This cytotoxin also possesses lytic activity on many other cells, including red blood cells. Interaction with sulfatides in the cell membrane induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It targets the mitochondrial membrane and induces mitochondrial swelling and fragmentation. Inhibits protein kinases C. It binds to the integrin alpha-V/beta-3 with a moderate affinity (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
