2mjy: Difference between revisions

Line 1:

'''~~Unreleased~~ structure'''

==Solution structure of synthetic Mamba-1 peptide==

== Structural highlights ==

<table><tr><td colspan='2'>[[2mjy]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MJY FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mjy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mjy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mjy RCSB], [http://www.ebi.ac.uk/pdbsum/2mjy PDBsum]</span></td></tr>

</table>

== Publication Abstract from PubMed ==

An efficient one-pot chemical synthesis of snake venom toxin Mambalgin-1 was achieved using an azide-switch strategy combined with hydrazide-based native chemical ligation. Synthetic Mambalgin-1 exhibited a well-defined structure after sequential folding in vitro. NMR spectroscopy revealed a three-finger toxin family structure, and the synthetic toxin inhibited human acid-sensing ion channel 1a.

~~The entry 2mjy is ON HOLD~~

One-pot hydrazide-based native chemical ligation for efficient chemical synthesis and structure determination of toxin Mambalgin-1.,Pan M, He Y, Wen M, Wu F, Sun D, Li S, Zhang L, Li Y, Tian C Chem Commun (Camb). 2014 Jun 4;50(44):5837-9. doi: 10.1039/c4cc00779d. PMID:24619065<ref>PMID:24619065</ref>

~~Authors: He~~, Y.~~, Wu, F~~.~~, Tian, C~~.

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

</div>

~~Description: Solution structure of synthetic Mamba-1 peptide~~

== References ==

[[Category: ~~Unreleased Structures~~]]

__TOC__

</StructureSection>

[[Category: He, Y]]

[[Category: Tian, C]]

[[Category: Wu, F]]

[[Category: ~~He, Y~~]]

[[Category: Manba]]

[[Category: Toxin]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Solution structure of synthetic Mamba-1 peptide==
+<StructureSection load='2mjy' size='340' side='right' caption='[[2mjy]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[2mjy]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MJY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MJY FirstGlance]. <br>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mjy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mjy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mjy RCSB], [http://www.ebi.ac.uk/pdbsum/2mjy PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+An efficient one-pot chemical synthesis of snake venom toxin Mambalgin-1 was achieved using an azide-switch strategy combined with hydrazide-based native chemical ligation. Synthetic Mambalgin-1 exhibited a well-defined structure after sequential folding in vitro. NMR spectroscopy revealed a three-finger toxin family structure, and the synthetic toxin inhibited human acid-sensing ion channel 1a.
-The entry 2mjy is ON HOLD
+One-pot hydrazide-based native chemical ligation for efficient chemical synthesis and structure determination of toxin Mambalgin-1.,Pan M, He Y, Wen M, Wu F, Sun D, Li S, Zhang L, Li Y, Tian C Chem Commun (Camb). 2014 Jun 4;50(44):5837-9. doi: 10.1039/c4cc00779d. PMID:24619065<ref>PMID:24619065</ref>
-Authors: He, Y., Wu, F., Tian, C.
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-Description: Solution structure of synthetic Mamba-1 peptide
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
+__TOC__
+</StructureSection>
+[[Category: He, Y]]
 [[Category: Tian, C]]
 [[Category: Wu, F]]
-[[Category: He, Y]]
+[[Category: Manba]]
+[[Category: Toxin]]