4cjx: Difference between revisions

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'''Unreleased structure'''
==The crystal structure of Trypanosoma brucei N5, N10- methylenetetrahydrofolate dehydrogenase-cyclohydrolase (FolD) complexed with NADP cofactor and inhibitor==
 
<StructureSection load='4cjx' size='340' side='right' caption='[[4cjx]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
The entry 4cjx is ON HOLD  until Paper Publication
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4cjx]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CJX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CJX FirstGlance]. <br>
Authors: Eadsforth, T.C., Hunter, W.N.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9L9:(2S)-2-[[4-[[2,4-BIS(AZANYL)-6-OXIDANYLIDENE-1H-PYRIMIDIN-5-YL]CARBAMOYLAMINO]PHENYL]CARBONYLAMINO]PENTANEDIOIC+ACID'>9L9</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
 
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylenetetrahydrofolate_dehydrogenase_(NADP(+)) Methylenetetrahydrofolate dehydrogenase (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.5 1.5.1.5] </span></td></tr>
Description: The crystal structure of Trypanosoma brucei N5, N10-methylenetetrahydrofolate dehydrogenase-cyclohydrolase (FolD) complexed with NADP cofactor and inhibitor
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cjx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cjx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cjx RCSB], [http://www.ebi.ac.uk/pdbsum/4cjx PDBsum]</span></td></tr>
[[Category: Unreleased Structures]]
</table>
[[Category: Hunter, W.N]]
__TOC__
[[Category: Eadsforth, T.C]]
</StructureSection>
[[Category: Eadsforth, T C]]
[[Category: Hunter, W N]]
[[Category: Oxidoreductase]]

Revision as of 15:53, 7 February 2015

The crystal structure of Trypanosoma brucei N5, N10- methylenetetrahydrofolate dehydrogenase-cyclohydrolase (FolD) complexed with NADP cofactor and inhibitor

4cjx, resolution 2.05Å

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