4ogk: Difference between revisions
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''' | ==X-ray structure of the uridine phosphorylase from Salmonella typhimurium in complex with thymidine at 2.40 A resolution== | ||
<StructureSection load='4ogk' size='340' side='right' caption='[[4ogk]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4ogk]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OGK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OGK FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=THM:THYMIDINE'>THM</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4e1v|4e1v]], [[4ogl|4ogl]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ogk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ogk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ogk RCSB], [http://www.ebi.ac.uk/pdbsum/4ogk PDBsum]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Lashkov, A | == Function == | ||
[[Category: Sotnichenko, S | [[http://www.uniprot.org/uniprot/UDP_SALTY UDP_SALTY]] Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity). | ||
[[Category: | __TOC__ | ||
</StructureSection> | |||
[[Category: Uridine phosphorylase]] | |||
[[Category: Gabdoulkhakov, A G]] | |||
[[Category: Lashkov, A A]] | |||
[[Category: Mikhailov, A M]] | |||
[[Category: Sotnichenko, S E]] | |||
[[Category: Phosphat-ion]] | |||
[[Category: Pirimidine nucleozide]] | |||
[[Category: Rossmann fold]] | |||
[[Category: Transferase]] | |||
Revision as of 11:32, 4 March 2015
X-ray structure of the uridine phosphorylase from Salmonella typhimurium in complex with thymidine at 2.40 A resolution
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