4q6a: Difference between revisions
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''' | ==Staphylococcus aureus V31L, F98Y Mutant Dihydrofolate Reductase Complexed with NADPH== | ||
<StructureSection load='4q6a' size='340' side='right' caption='[[4q6a]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4q6a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q6A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q6A FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q67|4q67]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q6a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q6a RCSB], [http://www.ebi.ac.uk/pdbsum/4q6a PDBsum]</span></td></tr> | ||
[[Category: Reeve, S | </table> | ||
[[Category: | == Function == | ||
[[http://www.uniprot.org/uniprot/W7NDF6_STAAU W7NDF6_STAAU]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[PIRNR:PIRNR000194] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Dihydrofolate reductase]] | |||
[[Category: Anderson, A C]] | |||
[[Category: Reeve, S M]] | |||
[[Category: Oxidoreductase]] | |||
Revision as of 14:52, 31 December 2014
Staphylococcus aureus V31L, F98Y Mutant Dihydrofolate Reductase Complexed with NADPH
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