4q6a: Difference between revisions

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'''Unreleased structure'''
==Staphylococcus aureus V31L, F98Y Mutant Dihydrofolate Reductase Complexed with NADPH==
 
<StructureSection load='4q6a' size='340' side='right' caption='[[4q6a]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
The entry 4q6a is ON HOLD  until Paper Publication
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4q6a]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4Q6A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4Q6A FirstGlance]. <br>
Authors: Reeve, S.M., Anderson, A.C.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4q67|4q67]]</td></tr>
Description: Staphylococcus aureus V31L, F98Y Mutant Dihydrofolate Reductase Complexed with NADPH
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3] </span></td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4q6a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4q6a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4q6a RCSB], [http://www.ebi.ac.uk/pdbsum/4q6a PDBsum]</span></td></tr>
[[Category: Reeve, S.M]]
</table>
[[Category: Anderson, A.C]]
== Function ==
[[http://www.uniprot.org/uniprot/W7NDF6_STAAU W7NDF6_STAAU]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.[PIRNR:PIRNR000194]
__TOC__
</StructureSection>
[[Category: Dihydrofolate reductase]]
[[Category: Anderson, A C]]
[[Category: Reeve, S M]]
[[Category: Oxidoreductase]]

Revision as of 14:52, 31 December 2014

Staphylococcus aureus V31L, F98Y Mutant Dihydrofolate Reductase Complexed with NADPH

4q6a, resolution 2.10Å

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