4r5u: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of Rhodostomin R46E mutant==

~~The entry~~ 4r5u is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4r5u]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R5U FirstGlance]. <br>

~~Authors~~: ~~Huang, C~~.H.~~, Shiu, J~~.H., ~~Chang, Y~~.T., ~~Jeng, W~~.Y., ~~Chuang, W~~.J.

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r5r|4r5r]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r5u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r5u RCSB], [http://www.ebi.ac.uk/pdbsum/4r5u PDBsum]</span></td></tr>

~~Description: Crystal structure of Rhodostomin R46E mutant~~

</table>

[[~~Category~~: ~~Unreleased Structures~~]]

== Function ==

~~[[Category~~: ~~Jeng~~, W.~~Y]]~~

[[http://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).

[[Category: Chang, Y.T]]

__TOC__

[[Category: Chuang, W.J]]

</StructureSection>

[[Category: Huang, C.H]]

[[Category: Chang, Y T]]

[[Category: Shiu, J.H]]

[[Category: Chuang, W J]]

[[Category: Huang, C H]]

[[Category: Jeng, W Y]]

[[Category: Shiu, J H]]

[[Category: Disintegrin]]

[[Category: Integrin]]

[[Category: Linker region]]

[[Category: Rgd motif]]

[[Category: Rhodostomin]]

[[Category: Toxin]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of Rhodostomin R46E mutant==
+<StructureSection load='4r5u' size='340' side='right' caption='[[4r5u]], [[Resolution|resolution]] 1.81&Aring;' scene=''>
-The entry 4r5u is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4r5u]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R5U OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R5U FirstGlance]. <br>
-Authors: Huang, C.H., Shiu, J.H., Chang, Y.T., Jeng, W.Y., Chuang, W.J.
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4r5r|4r5r]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r5u OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r5u RCSB], [http://www.ebi.ac.uk/pdbsum/4r5u PDBsum]</span></td></tr>
-Description: Crystal structure of Rhodostomin R46E mutant
+</table>
-[[Category: Unreleased Structures]]
+== Function ==
-[[Category: Jeng, W.Y]]
+[[http://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity).  Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).
-[[Category: Chang, Y.T]]
+__TOC__
-[[Category: Chuang, W.J]]
+</StructureSection>
-[[Category: Huang, C.H]]
+[[Category: Chang, Y T]]
-[[Category: Shiu, J.H]]
+[[Category: Chuang, W J]]
+[[Category: Huang, C H]]
+[[Category: Jeng, W Y]]
+[[Category: Shiu, J H]]
+[[Category: Disintegrin]]
+[[Category: Integrin]]
+[[Category: Linker region]]
+[[Category: Rgd motif]]
+[[Category: Rhodostomin]]
+[[Category: Toxin]]