4rau: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 4rau is ~~ON HOLD until Paper Publication~~

==crystal structure of RTOFab in complex with human PF4==

~~Authors~~: ~~Cai~~, Z., ~~Zhu~~, Z., ~~Liu, Q~~.~~, Greene, M~~.I.

== Structural highlights ==

<table><tr><td colspan='2'>[[4rau]] is a 24 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RAU FirstGlance]. <br>

~~Description~~: ~~crystal structure~~ of ~~RTOFab in complex with human PF4~~

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rau OCA], [http://pdbe.org/4rau PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rau RCSB], [http://www.ebi.ac.uk/pdbsum/4rau PDBsum]</span></td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

[[Category: Greene, M.I]]

== Function ==

[[http://www.uniprot.org/uniprot/PLF4_HUMAN PLF4_HUMAN]] Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.<ref>PMID:7644496</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Cai, Z]]

[[Category: Greene, M I]]

[[Category: Liu, Q]]

~~[[Category: Cai, Z]]~~

[[Category: Zhu, Z]]

[[Category: Antibody]]

[[Category: Antigen]]

[[Category: Blood]]

[[Category: Cxc chemokine]]

[[Category: Hit]]

[[Category: Immune system]]

[[Category: Immunoglobulin]]

[[Category: Pf4]]

[[Category: Rto]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4rau is ON HOLD  until Paper Publication
+==crystal structure of RTOFab in complex with human PF4==
+<StructureSection load='4rau' size='340' side='right' caption='[[4rau]], [[Resolution|resolution]] 3.74&Aring;' scene=''>
-Authors: Cai, Z., Zhu, Z., Liu, Q., Greene, M.I.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4rau]] is a 24 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RAU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RAU FirstGlance]. <br>
-Description: crystal structure of RTOFab in complex with human PF4
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rau OCA], [http://pdbe.org/4rau PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rau RCSB], [http://www.ebi.ac.uk/pdbsum/4rau PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Greene, M.I]]
+== Function ==
+[[http://www.uniprot.org/uniprot/PLF4_HUMAN PLF4_HUMAN]] Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.<ref>PMID:7644496</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Cai, Z]]
+[[Category: Greene, M I]]
 [[Category: Liu, Q]]
-[[Category: Cai, Z]]
 [[Category: Zhu, Z]]
+[[Category: Antibody]]
+[[Category: Antigen]]
+[[Category: Blood]]
+[[Category: Cxc chemokine]]
+[[Category: Hit]]
+[[Category: Immune system]]
+[[Category: Immunoglobulin]]
+[[Category: Pf4]]
+[[Category: Rto]]