4rij: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Crystal structure of the mtb phosphoenolpyruvate carboxykinase(pepck) in complex with gdp and metals==

~~The entry~~ 4rij is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4rij]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RIJ OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RIJ FirstGlance].

~~Authors~~: ~~Kim~~, H.L., ~~Kriger~~, I.V., ~~Sacchettini, J~~.C.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(GTP) Phosphoenolpyruvate carboxykinase (GTP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.32 4.1.1.32] </td></tr>

~~Description~~: ~~Crystal structure~~ of ~~the mtb~~ phosphoenolpyruvate ~~carboxykinase~~(~~pepck~~) in ~~complex with gdp~~ and ~~metals~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rij OCA], [http://pdbe.org/4rij PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rij RCSB], [http://www.ebi.ac.uk/pdbsum/4rij PDBsum]</td></tr>

[[~~Category~~: ~~Unreleased Structures]~~]

</table>

[[Category: Kim, H.L]]

== Function ==

[[Category: Kriger, I.V]]

[[http://www.uniprot.org/uniprot/I6Y334_MYCTU I6Y334_MYCTU]] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.[HAMAP-Rule:MF_00452]

[[Category: Sacchettini, J.C]]

__TOC__

</StructureSection>

[[Category: Kim, H L]]

[[Category: Kriger, I V]]

[[Category: Sacchettini, J C]]

[[Category: Gtp]]

[[Category: Gtp-dependent pepck]]

[[Category: Kinase]]

[[Category: Lyase]]

[[Category: Metal binding]]

[[Category: Phosphoryl transfer]]

[[Category: Rate-limiting gluconeogenic enzyme]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Crystal structure of the mtb phosphoenolpyruvate carboxykinase(pepck) in complex with gdp and metals==
+<StructureSection load='4rij' size='340' side='right' caption='[[4rij]], [[Resolution|resolution]] 2.12&Aring;' scene=''>
-The entry 4rij is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4rij]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RIJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RIJ FirstGlance]. <br>
-Authors: Kim, H.L., Kriger, I.V., Sacchettini, J.C.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(GTP) Phosphoenolpyruvate carboxykinase (GTP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.32 4.1.1.32] </span></td></tr>
-Description: Crystal structure of the mtb phosphoenolpyruvate carboxykinase(pepck) in complex with gdp and metals
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rij FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rij OCA], [http://pdbe.org/4rij PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rij RCSB], [http://www.ebi.ac.uk/pdbsum/4rij PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
-[[Category: Kim, H.L]]
+== Function ==
-[[Category: Kriger, I.V]]
+[[http://www.uniprot.org/uniprot/I6Y334_MYCTU I6Y334_MYCTU]] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.[HAMAP-Rule:MF_00452]
-[[Category: Sacchettini, J.C]]
+__TOC__
+</StructureSection>
+[[Category: Kim, H L]]
+[[Category: Kriger, I V]]
+[[Category: Sacchettini, J C]]
+[[Category: Gtp]]
+[[Category: Gtp-dependent pepck]]
+[[Category: Kinase]]
+[[Category: Lyase]]
+[[Category: Metal binding]]
+[[Category: Phosphoryl transfer]]
+[[Category: Rate-limiting gluconeogenic enzyme]]