4tlw: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==CARDS TOXIN, FULL-LENGTH==

~~The entry~~ 4tlw is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4tlw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TLW FirstGlance]. <br>

~~Authors~~: ~~Becker~~, A., ~~GALALELDEEN, A~~.~~, Taylor, A~~.B., ~~Hart, P~~.J.

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4tlv|4tlv]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tlw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tlw RCSB], [http://www.ebi.ac.uk/pdbsum/4tlw PDBsum]</span></td></tr>

~~Description:~~

</table>

[[~~Category~~: ~~Unreleased Structures~~]]

== Function ==

[[http://www.uniprot.org/uniprot/CARDS_MYCPN CARDS_MYCPN]] Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells.<ref>PMID:16617115</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Becker, A]]

[[Category: ~~Taylor~~, A.B]]

[[Category: GALALELDEEN, A]]

[[Category: Hart, P.J]]

[[Category: Hart, P J]]

[[Category: ~~Galaleldeen~~, A]]

[[Category: Taylor, A B]]

[[Category: Adp-ribosyl transferase]]

[[Category: Atypical pneumonia]]

[[Category: Community acquired respiratory distress syndrome]]

[[Category: Mycoplasma pneumoniae]]

[[Category: Toxin]]

[[Category: Transferase]]

[[Category: Virulence]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==CARDS TOXIN, FULL-LENGTH==
+<StructureSection load='4tlw' size='340' side='right' caption='[[4tlw]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
-The entry 4tlw is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4tlw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TLW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TLW FirstGlance]. <br>
-Authors: Becker, A., GALALELDEEN, A., Taylor, A.B., Hart, P.J.
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4tlv|4tlv]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tlw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tlw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tlw RCSB], [http://www.ebi.ac.uk/pdbsum/4tlw PDBsum]</span></td></tr>
-Description:
+</table>
-[[Category: Unreleased Structures]]
+== Function ==
+[[http://www.uniprot.org/uniprot/CARDS_MYCPN CARDS_MYCPN]] Acts as an ADP-ribosylating toxin, which may transfer the ADP-ribosyl group from NAD(+) to specific amino acids in target proteins. Elicits cytopathic effects in mammalian cells, such as disorganization and disruption of respiratory epithelial integrity in tracheal epithelium and vacuolization in the cytoplasm of CHO and HeLa cells.<ref>PMID:16617115</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Becker, A]]
-[[Category: Taylor, A.B]]
+[[Category: GALALELDEEN, A]]
-[[Category: Hart, P.J]]
+[[Category: Hart, P J]]
-[[Category: Galaleldeen, A]]
+[[Category: Taylor, A B]]
+[[Category: Adp-ribosyl transferase]]
+[[Category: Atypical pneumonia]]
+[[Category: Community acquired respiratory distress syndrome]]
+[[Category: Mycoplasma pneumoniae]]
+[[Category: Toxin]]
+[[Category: Transferase]]
+[[Category: Virulence]]