4u7b: Difference between revisions
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''' | ==Crystal structure of a pre-cleavage Mos1 transpososome== | ||
<StructureSection load='4u7b' size='340' side='right' caption='[[4u7b]], [[Resolution|resolution]] 3.09Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4u7b]] is a 9 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U7B OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U7B FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3hos|3hos]], [[3hot|3hot]], [[2f7t|2f7t]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u7b OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u7b RCSB], [http://www.ebi.ac.uk/pdbsum/4u7b PDBsum]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[http://www.uniprot.org/uniprot/MOS1T_DROMA MOS1T_DROMA]] Mediates transposition of transposon Mos1 by a 'cut and paste' mechanism. Transposases are sequence-specific nucleases and strand transferases that catalyze transposition through an ordered series of events: sequence-specific binding of transposase to the terminal inverted repeats (IR) present at each end of the transposon, pairing of the transposon IRs in a paired-end complex (PEC), cleavage of one or both DNA strands at each transposon end, capture of target DNA, and strand transfer to insert the transposon at a new site. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Richardson, J M]] | |||
[[Category: Dna transposition]] | |||
[[Category: Helix-turn-helix]] | |||
[[Category: Hydrolase-dna complex]] | |||
[[Category: Rnase-h like fold]] | |||
[[Category: Transposase]] | |||
[[Category: Transposon synaptic complex]] | |||