4u9m: Difference between revisions

Line 1:

'''~~Unreleased~~ structure'''

==Structure of the DNA duplex d(ATTAAT)2 with Hoogsteen hydrogen bonds==

== Structural highlights ==

<table><tr><td colspan='2'>[[4u9m]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U9M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U9M FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u9m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u9m RCSB], [http://www.ebi.ac.uk/pdbsum/4u9m PDBsum]</span></td></tr>

</table>

== Publication Abstract from PubMed ==

The traditional Watson-Crick base pairs in DNA may occasionally adopt a Hoogsteen conformation, with a different organization of hydrogen bonds. Previous crystal structures have shown that the Hoogsteen conformation is favored in alternating AT sequences of DNA. Here we present new data for a different sequence, d(ATTAAT)2, which is also found in the Hoogsteen conformation. Thus we demonstrate that other all-AT sequences of DNA with a different sequence may be found in the Hoogsteen conformation. We conclude that any all-AT sequence might acquire this conformation under appropriate conditions. We also compare the detailed features of DNA in either the Hoogsteen or Watson-Crick conformations.

~~The entry 4u9m is ON HOLD until Paper Publication~~

Structure of the DNA Duplex d(ATTAAT)2 with Hoogsteen Hydrogen Bonds.,Acosta-Reyes FJ, Alechaga E, Subirana JA, Campos JL PLoS One. 2015 Mar 17;10(3):e0120241. doi: 10.1371/journal.pone.0120241., eCollection 2015. PMID:25781995<ref>PMID:25781995</ref>

~~Authors: Acosta-Reyes~~, F.J.~~, Alechaga, E., Subirana, J.A., Campos, J.L~~.

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

</div>

~~Description: Structure of the DNA duplex d(ATTAAT)2 with Hoogsteen hydrogen bonds~~

== References ==

~~[[Category: Unreleased Structures]]~~

[[Category: Acosta-Reyes, F.J]]

__TOC__

~~[[Category: Subirana, J.A~~]]

</StructureSection>

[[Category: Acosta-Reyes, F J]]

[[Category: Alechaga, E]]

[[Category: Campos, J.L]]

[[Category: Campos, J L]]

[[Category: Subirana, J A]]

[[Category: Dna]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Structure of the DNA duplex d(ATTAAT)2 with Hoogsteen hydrogen bonds==
+<StructureSection load='4u9m' size='340' side='right' caption='[[4u9m]], [[Resolution|resolution]] 3.13&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4u9m]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U9M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U9M FirstGlance]. <br>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u9m OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u9m RCSB], [http://www.ebi.ac.uk/pdbsum/4u9m PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The traditional Watson-Crick base pairs in DNA may occasionally adopt a Hoogsteen conformation, with a different organization of hydrogen bonds. Previous crystal structures have shown that the Hoogsteen conformation is favored in alternating AT sequences of DNA. Here we present new data for a different sequence, d(ATTAAT)2, which is also found in the Hoogsteen conformation. Thus we demonstrate that other all-AT sequences of DNA with a different sequence may be found in the Hoogsteen conformation. We conclude that any all-AT sequence might acquire this conformation under appropriate conditions. We also compare the detailed features of DNA in either the Hoogsteen or Watson-Crick conformations.
-The entry 4u9m is ON HOLD  until Paper Publication
+Structure of the DNA Duplex d(ATTAAT)2 with Hoogsteen Hydrogen Bonds.,Acosta-Reyes FJ, Alechaga E, Subirana JA, Campos JL PLoS One. 2015 Mar 17;10(3):e0120241. doi: 10.1371/journal.pone.0120241., eCollection 2015. PMID:25781995<ref>PMID:25781995</ref>
-Authors: Acosta-Reyes, F.J., Alechaga, E., Subirana, J.A., Campos, J.L.
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
-Description: Structure of the DNA duplex d(ATTAAT)2 with Hoogsteen hydrogen bonds
+== References ==
-[[Category: Unreleased Structures]]
+<references/>
-[[Category: Acosta-Reyes, F.J]]
+__TOC__
-[[Category: Subirana, J.A]]
+</StructureSection>
+[[Category: Acosta-Reyes, F J]]
 [[Category: Alechaga, E]]
-[[Category: Campos, J.L]]
+[[Category: Campos, J L]]
+[[Category: Subirana, J A]]
+[[Category: Dna]]