4u9y: Difference between revisions
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''' | ==Structure of the alpha-tubulin acetyltransferase alpha-TAT1/Mec-17 in complex with CoA== | ||
<StructureSection load='4u9y' size='340' side='right' caption='[[4u9y]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4u9y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U9Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U9Y FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vwd|3vwd]], [[3vwe|3vwe]], [[4u9z|4u9z]]</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alpha-tubulin_N-acetyltransferase Alpha-tubulin N-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.108 2.3.1.108] </span></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u9y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4u9y RCSB], [http://www.ebi.ac.uk/pdbsum/4u9y PDBsum]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ATAT_HUMAN ATAT_HUMAN]] Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. May affect microtubule stability and regulate microtubule dynamics. May be involved in neuron development.<ref>PMID:20829795</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Alpha-tubulin N-acetyltransferase]] | |||
[[Category: Sumimoto, H]] | |||
[[Category: Yuzawa, S]] | [[Category: Yuzawa, S]] | ||
[[Category: | [[Category: Gnat superfamily fold]] | ||
[[Category: Transferase]] | |||
Revision as of 14:47, 12 August 2015
Structure of the alpha-tubulin acetyltransferase alpha-TAT1/Mec-17 in complex with CoA
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