1ytf: Difference between revisions
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|PDB= 1ytf |SIZE=350|CAPTION= <scene name='initialview01'>1ytf</scene>, resolution 2.500Å | |PDB= 1ytf |SIZE=350|CAPTION= <scene name='initialview01'>1ytf</scene>, resolution 2.500Å | ||
|SITE= | |SITE= | ||
|LIGAND= | |LIGAND= <scene name='pdbligand=DA:2'-DEOXYADENOSINE-5'-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ytf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ytf OCA], [http://www.ebi.ac.uk/pdbsum/1ytf PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1ytf RCSB]</span> | |||
}} | }} | ||
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[[Category: transcription regulation]] | [[Category: transcription regulation]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:21:32 2008'' | ||
Revision as of 22:21, 30 March 2008
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| 1ytf, resolution 2.500Å | |||||||||||||
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| Ligands: | DA, DC, DG, DT | ||||||||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
YEAST TFIIA/TBP/DNA COMPLEX
Overview
The X-ray crystal structure of the transcription factor IIA (TFIIA) in complex with the TATA-box-binding protein (TBP) and TATA-element DNA is presented at 2.5 A resolution. TFIIA is composed of a beta-barrel and a four-helix bundle motif that together have a boot-like appearance. The beta-barrel extends the TBP beta-sheet and bridges over the DNA major groove immediately upstream of the TATA box. The four-helix bundle contributes substantially to the surface of the complex available for interaction with additional transcription factors.
About this Structure
1YTF is a Protein complex structure of sequences from Saccharomyces cerevisiae. The following page contains interesting information on the relation of 1YTF with [TATA-Binding Protein]. Full crystallographic information is available from OCA.
Reference
Crystal structure of a yeast TFIIA/TBP/DNA complex., Tan S, Hunziker Y, Sargent DF, Richmond TJ, Nature. 1996 May 9;381(6578):127-51. PMID:8610010
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