4v0r: Difference between revisions
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''' | ==DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH== | ||
<StructureSection load='4v0r' size='340' side='right' caption='[[4v0r]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4v0r]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V0R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4V0R FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4v0q|4v0q]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4v0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v0r OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4v0r RCSB], [http://www.ebi.ac.uk/pdbsum/4v0r PDBsum]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: Lim, S | == Function == | ||
[[http://www.uniprot.org/uniprot/Q6DLV0_9FLAV Q6DLV0_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Cornvik, T C]] | |||
[[Category: Lescar, J]] | |||
[[Category: Lim, S P]] | |||
[[Category: Luo, D]] | |||
[[Category: Phoo, W W]] | |||
[[Category: Shi, P Y]] | |||
[[Category: Soh, S]] | [[Category: Soh, S]] | ||
[[Category: Swaminathan, K]] | [[Category: Swaminathan, K]] | ||
[[Category: | [[Category: Vasudevan, S G]] | ||
[[Category: Zhao, Y]] | [[Category: Zhao, Y]] | ||
[[Category: Zheng, J]] | [[Category: Zheng, J]] | ||
[[Category: | [[Category: Methyltransferase]] | ||
[[Category: Rna-dependent rna polymerase]] | |||
[[Category: Transferase]] | |||
Revision as of 16:49, 28 January 2015
DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH
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