4w59: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==T4 Lysozyme L99A with n-Hexylbenzene Bound==

~~The entry~~ 4w59 is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4w59]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W59 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W59 FirstGlance].

~~Authors~~: ~~Merski~~, M., ~~Shoichet~~, B.K., ~~Eidam, O~~., ~~Fischer, M~~.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=3GZ:HEXYLBENZENE'>3GZ</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </td></tr>

~~Description~~: T4 Lysozyme ~~L99A with n-Hexylbenzene Bound~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w59 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4w59 RCSB], [http://www.ebi.ac.uk/pdbsum/4w59 PDBsum]</td></tr>

[[Category: ~~Unreleased Structures~~]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4]] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Lysozyme]]

[[Category: Eidam, O]]

[[Category: Fischer, M]]

[[Category: Merski, M]]

~~[[Category: Fischer, M]]~~

[[Category: Shoichet, B K]]

[[Category: Shoichet, B.K]]

[[Category: Hydrolase]]

[[Category: ~~Eidam, O~~]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==T4 Lysozyme L99A with n-Hexylbenzene Bound==
+<StructureSection load='4w59' size='340' side='right' caption='[[4w59]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
-The entry 4w59 is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4w59]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4W59 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4W59 FirstGlance]. <br>
-Authors: Merski, M., Shoichet, B.K., Eidam, O., Fischer, M.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3GZ:HEXYLBENZENE'>3GZ</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-Description: T4 Lysozyme L99A with n-Hexylbenzene Bound
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4w59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4w59 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4w59 RCSB], [http://www.ebi.ac.uk/pdbsum/4w59 PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4]] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Lysozyme]]
+[[Category: Eidam, O]]
+[[Category: Fischer, M]]
 [[Category: Merski, M]]
-[[Category: Fischer, M]]
+[[Category: Shoichet, B K]]
-[[Category: Shoichet, B.K]]
+[[Category: Hydrolase]]
-[[Category: Eidam, O]]