4wpu: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 4wpu is ~~ON HOLD until Paper Publication~~

==Crystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDP==

== Structural highlights ==

<table><tr><td colspan='2'>[[4wpu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycta Mycta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WPU OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WPU FirstGlance].

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene></td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">pckG, MRA_0219 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=419947 MYCTA])</td></tr>

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(GTP) Phosphoenolpyruvate carboxykinase (GTP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.32 4.1.1.32] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wpu OCA], [http://pdbe.org/4wpu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wpu RCSB], [http://www.ebi.ac.uk/pdbsum/4wpu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wpu ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/PCKG_MYCTA PCKG_MYCTA]] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.

~~Authors~~: Kim, H.L., Sacchettini, J.C.

==See Also==

*[[Phosphoenolpyruvate carboxykinase|Phosphoenolpyruvate carboxykinase]]

~~Description~~: ~~Crystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDP~~

__TOC__

[[Category: ~~Unreleased Structures~~]]

</StructureSection>

[[Category: ~~Sacchettini, J.C~~]]

[[Category: Large Structures]]

[[Category: ~~Kim, H.L~~]]

[[Category: Mycta]]

[[Category: Kim, H L]]

[[Category: Sacchettini, J C]]

[[Category: Anaplerotic reaction]]

[[Category: Gtp-dependent pepck]]

[[Category: Lyase]]

[[Category: Omega-loop]]

[[Category: P-loop]]

[[Category: R-loop]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 4wpu is ON HOLD  until Paper Publication
+==Crystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDP==
+<StructureSection load='4wpu' size='340' side='right'caption='[[4wpu]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4wpu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycta Mycta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WPU FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4wiu|4wiu]], [[4wpt|4wpt]], [[4wou|4wou]], [[4wpv|4wpv]], [[4wie|4wie]], [[4wl8|4wl8]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pckG, MRA_0219 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=419947 MYCTA])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoenolpyruvate_carboxykinase_(GTP) Phosphoenolpyruvate carboxykinase (GTP)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.32 4.1.1.32] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wpu OCA], [http://pdbe.org/4wpu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wpu RCSB], [http://www.ebi.ac.uk/pdbsum/4wpu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wpu ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/PCKG_MYCTA PCKG_MYCTA]] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
-Authors: Kim, H.L., Sacchettini, J.C.
+==See Also==
+*[[Phosphoenolpyruvate carboxykinase|Phosphoenolpyruvate carboxykinase]]
-Description: Crystal Structure of E83A mutant of Mtb PEPCK in complex with PEP and GDP
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Sacchettini, J.C]]
+[[Category: Large Structures]]
-[[Category: Kim, H.L]]
+[[Category: Mycta]]
+[[Category: Kim, H L]]
+[[Category: Sacchettini, J C]]
+[[Category: Anaplerotic reaction]]
+[[Category: Gtp-dependent pepck]]
+[[Category: Lyase]]
+[[Category: Omega-loop]]
+[[Category: P-loop]]
+[[Category: R-loop]]
+[[Category: Transferase]]