4wq2: Difference between revisions

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'''Unreleased structure'''
==Human calpain PEF(S) with (Z)-3-(6-bromondol-3-yl)-2-mercaptoacrylic acid bound==
 
<StructureSection load='4wq2' size='340' side='right' caption='[[4wq2]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
The entry 4wq2 is ON HOLD  until Paper Publication
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4wq2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WQ2 FirstGlance]. <br>
Authors: Adams, S.E., Rizkallah, P.J., Miller, D.J., Hallett, M.B., Allemann, R.K.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3SU:(2Z)-3-(6-BROMO-1H-INDOL-3-YL)-2-SULFANYLPROP-2-ENOIC+ACID'>3SU</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wq2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wq2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wq2 RCSB], [http://www.ebi.ac.uk/pdbsum/4wq2 PDBsum]</span></td></tr>
Description: Human calpain PEF(S) with (Z)-3-(6-bromondol-3-yl)-2-mercaptoacrylic acid bound
</table>
[[Category: Unreleased Structures]]
== Function ==
[[Category: Miller, D.J]]
[[http://www.uniprot.org/uniprot/CPNS1_HUMAN CPNS1_HUMAN]] Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.
[[Category: Rizkallah, P.J]]
__TOC__
[[Category: Allemann, R.K]]
</StructureSection>
[[Category: Hallett, M.B]]
[[Category: Adams, S E]]
[[Category: Adams, S.E]]
[[Category: Allemann, R K]]
[[Category: Hallett, M B]]
[[Category: Miller, D J]]
[[Category: Rizkallah, P J]]
[[Category: Calcium binding]]
[[Category: Calpain]]
[[Category: Domain vi]]
[[Category: Ef-hand]]
[[Category: Human]]
[[Category: Hydrolase]]
[[Category: Protease]]