4x1j: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==X-ray crystal structure of the dimeric BMP antagonist NBL1==

~~The entry~~ 4x1j is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4x1j]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X1J OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X1J FirstGlance].

~~Authors~~: ~~Thompason~~, T.B., ~~Nolan~~, K.~~, Kattamuri, C~~.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4jph|4jph]]</td></tr>

~~Description: X-ray crystal structure of the dimeric BMP antagonist NBL1~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x1j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x1j RCSB], [http://www.ebi.ac.uk/pdbsum/4x1j PDBsum]</td></tr>

[[~~Category~~: ~~Unreleased Structures~~]]

</table>

== Function ==

[[http://www.uniprot.org/uniprot/NBL1_HUMAN NBL1_HUMAN]] Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process.

__TOC__

</StructureSection>

[[Category: Kattamuri, C]]

[[Category: Nolan, K]]

[[Category: Thompason, T.B]]

[[Category: Thompason, T B]]

[[Category: Bmp antagonist]]

[[Category: Bmp binding protein]]

[[Category: Cystine-knot]]

[[Category: Dan family]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==X-ray crystal structure of the dimeric BMP antagonist NBL1==
+<StructureSection load='4x1j' size='340' side='right' caption='[[4x1j]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-The entry 4x1j is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4x1j]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X1J OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X1J FirstGlance]. <br>
-Authors: Thompason, T.B., Nolan, K., Kattamuri, C.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jph|4jph]]</td></tr>
-Description: X-ray crystal structure of the dimeric BMP antagonist NBL1
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x1j OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x1j RCSB], [http://www.ebi.ac.uk/pdbsum/4x1j PDBsum]</span></td></tr>
-[[Category: Unreleased Structures]]
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/NBL1_HUMAN NBL1_HUMAN]] Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process.
+__TOC__
+</StructureSection>
 [[Category: Kattamuri, C]]
 [[Category: Nolan, K]]
-[[Category: Thompason, T.B]]
+[[Category: Thompason, T B]]
+[[Category: Bmp antagonist]]
+[[Category: Bmp binding protein]]
+[[Category: Cystine-knot]]
+[[Category: Dan family]]