211d: Difference between revisions
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|PDB= 211d |SIZE=350|CAPTION= <scene name='initialview01'>211d</scene>, resolution 1.600Å | |PDB= 211d |SIZE=350|CAPTION= <scene name='initialview01'>211d</scene>, resolution 1.600Å | ||
|SITE= | |SITE= | ||
|LIGAND= <scene name='pdbligand=PTN:PLATINUM+TRIAMINE+ION'>PTN</scene> | |LIGAND= <scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene>, <scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5'-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=PTN:PLATINUM+TRIAMINE+ION'>PTN</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene> | ||
|ACTIVITY= | |ACTIVITY= | ||
|GENE= | |GENE= | ||
|DOMAIN= | |||
|RELATEDENTRY= | |||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=211d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=211d OCA], [http://www.ebi.ac.uk/pdbsum/211d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=211d RCSB]</span> | |||
}} | }} | ||
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[[Category: Lessinger, L.]] | [[Category: Lessinger, L.]] | ||
[[Category: Parkinson, G N.]] | [[Category: Parkinson, G N.]] | ||
[[Category: double helix]] | [[Category: double helix]] | ||
[[Category: modified]] | [[Category: modified]] | ||
[[Category: z-dna]] | [[Category: z-dna]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:44:15 2008'' | ||
Revision as of 22:44, 30 March 2008
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| 211d, resolution 1.600Å | |||||||||||||
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| Ligands: | 1AP, DC, DG, DT, PTN, SPM | ||||||||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE
Overview
The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was determined to atomic (1.35 A) resolution by single isomorphous replacement. The d[CGTA'CG] hexamer crystallizes in space group P3221, and is not isomorphous with other DNA hexanucleotides. Despite completely different crystal packing, the essential characteristics of the Z-DNA conformation are maintained. The structure was determined by single isomorphous replacement using a triammine platinum fragment. Thus, this study also demonstrates, for the first time, the feasibility of the use of this reagent for the direct phasing of DNA crystal structures.
About this Structure
211D is a Protein complex structure of sequences from [1]. Full crystallographic information is available from OCA.
Reference
Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative., Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM, Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:7492550
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