1jc6: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1jc6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bungarus_fasciatus Bungarus fasciatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JC6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JC6 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1jc6]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bungarus_fasciatus Bungarus fasciatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JC6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JC6 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jc6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jc6 RCSB], [http://www.ebi.ac.uk/pdbsum/1jc6 PDBsum]</span></td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jc6 OCA], [http://pdbe.org/1jc6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jc6 RCSB], [http://www.ebi.ac.uk/pdbsum/1jc6 PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/ | [[http://www.uniprot.org/uniprot/VKT9_BUNFA VKT9_BUNFA]] Dual-function toxin that inhibits both serine proteases (high activity on chymotrypsin (Ki = 18 nM), and low activity on elastase) and voltage-gated potassium channels Kv1.3/KCNA3 (IC(50) = 120.0 nM).<ref>PMID:11562364</ref> <ref>PMID:24243656</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 1jc6" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
