2bxt: Difference between revisions

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|PDB= 2bxt |SIZE=350|CAPTION= <scene name='initialview01'>2bxt</scene>, resolution 1.83&Aring;
|PDB= 2bxt |SIZE=350|CAPTION= <scene name='initialview01'>2bxt</scene>, resolution 1.83&Aring;
|SITE= <scene name='pdbsite=AC1:C2d+Binding+Site+For+Chain+H'>AC1</scene>
|SITE= <scene name='pdbsite=AC1:C2d+Binding+Site+For+Chain+H'>AC1</scene>
|LIGAND= <scene name='pdbligand=C2D:6-CHLORO-1-(2-{[(5-CHLORO-1-BENZOTHIEN-3-YL)METHYL]AMINO}ETHYL)-3-[(2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL'>C2D</scene>
|LIGAND= <scene name='pdbligand=C2D:6-CHLORO-1-(2-{[(5-CHLORO-1-BENZOTHIEN-3-YL)METHYL]AMINO}ETHYL)-3-[(2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL'>C2D</scene>, <scene name='pdbligand=TYS:SULFONATED+TYROSINE'>TYS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] </span>
|GENE=  
|GENE=  
|DOMAIN=
|RELATEDENTRY=
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bxt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bxt OCA], [http://www.ebi.ac.uk/pdbsum/2bxt PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2bxt RCSB]</span>
}}
}}


'''DESIGN AND DISCOVERY OF NOVEL, POTENT THROMBIN INHIBITORS WITH A SOLUBILIZING CATIONIC P1-P2-LINKER'''
'''DESIGN AND DISCOVERY OF NOVEL, POTENT THROMBIN INHIBITORS WITH A SOLUBILIZING CATIONIC P1-P2-LINKER'''


==Disease==
Known diseases associated with this structure: Dysprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hyperprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]], Hypoprothrombinemia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176930 176930]]


==About this Structure==
==About this Structure==
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[[Category: Schamberger, J.]]
[[Category: Schamberger, J.]]
[[Category: Sekul, R.]]
[[Category: Sekul, R.]]
[[Category: C2D]]
[[Category: hydrolase]]
[[Category: hydrolase]]
[[Category: serine proteinase]]
[[Category: serine proteinase]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:13:20 2008''
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