4l93: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of Human Hsp90 with S36== | ==Crystal structure of Human Hsp90 with S36== | ||
<StructureSection load='4l93' size='340' side='right' caption='[[4l93]], [[Resolution|resolution]] 1.84Å' scene=''> | <StructureSection load='4l93' size='340' side='right' caption='[[4l93]], [[Resolution|resolution]] 1.84Å' scene=''> | ||
| Line 5: | Line 6: | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S36:3,4-DIHYDROISOQUINOLIN-2(1H)-YL[2,4-DIHYDROXY-5-(PROPAN-2-YL)PHENYL]METHANONE'>S36</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S36:3,4-DIHYDROISOQUINOLIN-2(1H)-YL[2,4-DIHYDROXY-5-(PROPAN-2-YL)PHENYL]METHANONE'>S36</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4l8z|4l8z]], [[4l90|4l90]], [[4l91|4l91]], [[4l94|4l94]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4l8z|4l8z]], [[4l90|4l90]], [[4l91|4l91]], [[4l94|4l94]]</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l93 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4l93 RCSB], [http://www.ebi.ac.uk/pdbsum/4l93 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4l93 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l93 OCA], [http://pdbe.org/4l93 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4l93 RCSB], [http://www.ebi.ac.uk/pdbsum/4l93 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4l93 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref> | [[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref> | ||
==See Also== | |||
*[[Heat Shock Proteins|Heat Shock Proteins]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
Revision as of 15:16, 4 August 2016
Crystal structure of Human Hsp90 with S36
| ||||||||||||
