3dok: Difference between revisions
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==Crystal structure of K103N mutant HIV-1 reverse transcriptase in complex with GW678248.== | ==Crystal structure of K103N mutant HIV-1 reverse transcriptase in complex with GW678248.== | ||
<StructureSection load='3dok' size='340' side='right' caption='[[3dok]], [[Resolution|resolution]] 2.90Å' scene=''> | <StructureSection load='3dok' size='340' side='right' caption='[[3dok]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3dok]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3dok]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hiv-1 Hiv-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DOK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DOK FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GWJ:2-{4-CHLORO-2-[(3-CHLORO-5-CYANOPHENYL)CARBONYL]PHENOXY}-N-(2-METHYL-4-SULFAMOYLPHENYL)ACETAMIDE'>GWJ</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GWJ:2-{4-CHLORO-2-[(3-CHLORO-5-CYANOPHENYL)CARBONYL]PHENOXY}-N-(2-METHYL-4-SULFAMOYLPHENYL)ACETAMIDE'>GWJ</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dle|3dle]], [[3dlg|3dlg]], [[3dm2|3dm2]], [[3dmj|3dmj]], [[3dol|3dol]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dle|3dle]], [[3dlg|3dlg]], [[3dm2|3dm2]], [[3dmj|3dmj]], [[3dol|3dol]]</td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id= | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gag-pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11706 HIV-1])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dok FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dok OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3dok RCSB], [http://www.ebi.ac.uk/pdbsum/3dok PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dok FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dok OCA], [http://pdbe.org/3dok PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dok RCSB], [http://www.ebi.ac.uk/pdbsum/3dok PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3dok ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
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<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3dok ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 3dok" style="background-color:#fffaf0;"></div> | |||
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Hiv-1]] | ||
[[Category: Chamberlain, P P]] | [[Category: Chamberlain, P P]] | ||
[[Category: Ren, J]] | [[Category: Ren, J]] | ||