3ba1: Difference between revisions

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==Structure of hydroxyphenylpyruvate reductase from coleus blumei==
==Structure of hydroxyphenylpyruvate reductase from coleus blumei==
<StructureSection load='3ba1' size='340' side='right' caption='[[3ba1]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
<StructureSection load='3ba1' size='340' side='right' caption='[[3ba1]], [[Resolution|resolution]] 1.47&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3ba1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Solenostemon_scutellarioides Solenostemon scutellarioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BA1 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3ba1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Coleus Coleus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BA1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3BA1 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hppr ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4142 Solenostemon scutellarioides])</td></tr>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hppr ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4142 Coleus])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxyphenylpyruvate_reductase Hydroxyphenylpyruvate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.237 1.1.1.237] </span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydroxyphenylpyruvate_reductase Hydroxyphenylpyruvate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.237 1.1.1.237] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ba1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ba1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ba1 RCSB], [http://www.ebi.ac.uk/pdbsum/3ba1 PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ba1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ba1 OCA], [http://pdbe.org/3ba1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3ba1 RCSB], [http://www.ebi.ac.uk/pdbsum/3ba1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3ba1 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q65CJ7_SOLSC Q65CJ7_SOLSC]] Catalyzes the NAD(P)H-dependent reduction of 4-hydroxyphenylpyruvate to 4-hydroxyphenyllactate and 3,4-dihydroxyphenylpyruvate to 3,4-dihydroxyphenyllactate in the biosynthesis of rosmarinic acid. Rosmarinic acid is an ester of caffeic acid and 3,4-dihydroxyphenyllactic acid. NADP is the preferred substrate.  
[[http://www.uniprot.org/uniprot/HPPR_PLESU HPPR_PLESU]] Catalyzes the NAD(P)H-dependent reduction of 4-hydroxyphenylpyruvate to 4-hydroxyphenyllactate and 3,4-dihydroxyphenylpyruvate to 3,4-dihydroxyphenyllactate in the biosynthesis of rosmarinic acid. Rosmarinic acid is an ester of caffeic acid and 3,4-dihydroxyphenyllactic acid. NADP is the preferred substrate.<ref>PMID:15284489</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ba1 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Coleus]]
[[Category: Hydroxyphenylpyruvate reductase]]
[[Category: Hydroxyphenylpyruvate reductase]]
[[Category: Solenostemon scutellarioides]]
[[Category: Heine, A]]
[[Category: Heine, A]]
[[Category: Janiak, V]]
[[Category: Janiak, V]]