Exoenzyme: Difference between revisions

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<StructureSection load='2c8c' size='340' side='right' caption='Structure of exoenzyme C3 catalytic domain complex with ADP and NAD (PDB code [[2c8c]]).' scene=''>
<StructureSection load='2c8c' size='340' side='right' caption='Structure of exoenzyme C3 catalytic domain complex with ADP and NAD (PDB code [[2c8c]]).' scene=''>


== Function ==
'''Exoenzymes''' (Exo) are secreted by cells and break large macromolecules outside the cells.  The breakdown components can pass through the cell wall.  '''Exo C3''' is a ''Clostridium butulinum'' toxin which binds NAD, splits it into ADP-ribose and nicotinamide and transfers the ADP-ribose to a protein substrate.  '''Exo S''' and '''Exo T''' are secreted by ''Pseudomonas aeruginosa'' and has GTPase-activating activity as well as ADP-ribosyltransferase activity<ref>PMID:11114250</ref> .


'''Exoenzymes''' (Exo) are secreted by cells and break large macromolecules outside the cells.  The breakdown components can pass through the cell wall.  '''Exo C3''' is a ''Clostridium butulinum'' toxin which binds NAD, splits it into ADP-ribose and nicotinamide and transfers the ADP-ribose to a protein substrate.  '''Exo S''' and '''Exo T''' are secreted by ''Pseudomonas aeruginosa'' and has GTPase-activating activity as well as ADP-ribosyltransferase activity.
== Disease ==
== Relevance ==
== Structural highlights ==
</StructureSection>
</StructureSection>


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