Practical Guide to Homology Modeling: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Eric Martz (talk | contribs) |
Eric Martz (talk | contribs) |
||
| Line 19: | Line 19: | ||
Here are two methods for finding out if your query amino acid sequence, or parts of it, have empirically-determined 3D structures in the PDB. | Here are two methods for finding out if your query amino acid sequence, or parts of it, have empirically-determined 3D structures in the PDB. | ||
=== Simple search for empirical models (via PIR) === | |||
At UniProt.Org, find your protein and click on Structure. | |||
*If there is a column labeled “Entry” with 4-character PDB IDs, these are empirical structures for your protein. Pay attention to the “Positions” column, which gives the sequence number range covered by each model. | |||
*If there is no “Entry” column, then there are no sequence-identical empirical structures for your protein. Then try the Advanced search method below. | |||
*Some proteins have no Structure section (e.g. K4QDG1_SACBA). Then try the Advanced search method below. | |||
If empirical structures exist, see sections below for guidance on how to explore them. If they are satisfactory, then you don't need a homology model. | |||
== References == | == References == | ||
<references/> | <references/> | ||
