Sandbox Reserved 962: Difference between revisions

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=== Interaction with a Cap Analogue (7-methylguanosine-5-triphosphate-5-Guanosine)===  
=== Interaction with a Cap Analogue (7-methylguanosine-5-triphosphate-5-Guanosine)===  


<scene name='60/604481/Gtg/2'>TextToBeDisplayed</scene>
<scene name='60/604481/Gtg/2'>Cap analogue</scene>


===Interaction with AdoHcy (S-adenosyl-L-homocysteine)===
===Interaction with AdoHcy (S-adenosyl-L-homocysteine)===
 
The mRNA Cap Methyltransferase bind to <scene name='60/604481/Sah/1'>AdoHcy</scene> which is the product of the methyl donor AdoMet after the methylation.
<scene name='60/604481/Sah/1'>TextToBeDisplayed</scene>
Adohcys is in a pocket formed by amino acids of segment 2.
10 amino acids are involved in the stabilisation of AdoHcys.
The interactions between AdoHcys and the enzyme are made of hydrogen bons, Van der Walls interactions,electrostatic interaction and water mediated contact.


== Post transcriptional modifications==
== Post transcriptional modifications==