Tachyplesin: Difference between revisions
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== Possible Function as antitumor peptide == | == Possible Function as antitumor peptide == | ||
The cationic nature of tachyplesin allows it to interact with anionic phospholipids present in the bacterial membrane and thereby disrupt membrane function. | The cationic nature of tachyplesin allows it to interact with anionic phospholipids present in the bacterial membrane and thereby disrupt membrane function. <ref name=Saravanan>PMID:22464970</ref> | ||
The structural nature of tachyplesin suggested that it might also posses antitumor properties. Since it can interact with the membrance of prokaryotic cell, it is likely that TP I can also interact with the mitochondrial membrane of eukaryotic cells due to the structure similarity of these membranes because mitochondria are widely belived to have evolved from prokaryotic cells that have established a symbiotic relationship with the promitive eukaryotic cell. | The structural nature of tachyplesin suggested that it might also posses antitumor properties. Since it can interact with the membrance of prokaryotic cell, it is likely that TP I can also interact with the mitochondrial membrane of eukaryotic cells due to the structure similarity of these membranes because mitochondria are widely belived to have evolved from prokaryotic cells that have established a symbiotic relationship with the promitive eukaryotic cell. | ||