Practical Guide to Homology Modeling: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Eric Martz (talk | contribs) |
Eric Martz (talk | contribs) |
||
| Line 210: | Line 210: | ||
| Hydrophobic catalytic face of lipase ([[1lpm]]). | | Hydrophobic catalytic face of lipase ([[1lpm]]). | ||
| Transmembrane protein ([[3waj]]). | | Transmembrane protein ([[3waj]]). | ||
|} | |||
</center> | |||
===Hydrophobic Core=== | |||
Soluble proteins should have a well-defined hydrophobic core. To see this in ''FirstGlance'', under the ''Views'' tab, click ''Hydrophobic/Polar'', and then turn on the ''Slab'' button. If the protein has multiple domains, each domain should have a hydrophobic core. If there is no hydrophobic core in a soluble protein model, the model most likely has very substantial errors. | |||
<center> | |||
{| class="wikitable" | |||
|- | |||
! colspan="1" | <span style="font-size:150%;">{{Template:ColorKey_Hydrophobic}}, {{Template:ColorKey_Polar}}</span> | |||
|- | |||
| [[Image:Hydrophobic-cores.png]] | |||
|- | |||
| Hydrophobic cores in domains (circled in <font color="red">'''red'''</font>; [[4cpa]]). | |||
|} | |} | ||
