4uf0: Difference between revisions

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'''Unreleased structure'''
==Crystal structure of JmjC domain of human histone demethylase UTY in complex with epitherapuetic compound 2-(((2-((2-(dimethylamino)ethyl) (ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid.==
 
<StructureSection load='4uf0' size='340' side='right' caption='[[4uf0]], [[Resolution|resolution]] 1.78&Aring;' scene=''>
The entry 4uf0 is ON HOLD
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4uf0]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UF0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UF0 FirstGlance]. <br>
Authors: SRIKANNATHASAN, V., JOHANSSON, C., GILEADI, C., TOBIAS, K., KOPEC, J., VON DELFT, F., ARROWSMITH, C.H., BOUNTRA, C., EDWARDS, A., OPPERMANN, U.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=MMK:2-{[(2-{[(E)-2-(DIMETHYLAMINO)ETHENYL](ETHYL)AMINO}-2-OXOETHYL)AMINO]METHYL}PYRIDINE-4-CARBOXYLIC+ACID'>MMK</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uf0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uf0 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uf0 RCSB], [http://www.ebi.ac.uk/pdbsum/4uf0 PDBsum]</span></td></tr>
Description: Crystal structure of JmjC domain of human histone demethylase UTY in complex with epitherapuetic compound 2-(((2-((2-(dimethylamino)ethyl) (ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid.
</table>
[[Category: Unreleased Structures]]
== Function ==
[[Category: Tobias, K]]
[[http://www.uniprot.org/uniprot/UTY_HUMAN UTY_HUMAN]] Histone demethylase (By similarity).
__TOC__
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Bountra, C]]
[[Category: Arrowsmith, C.H]]
[[Category: Delft, F Von]]
[[Category: Edwards, A]]
[[Category: Gileadi, C]]
[[Category: Gileadi, C]]
[[Category: Johansson, C]]
[[Category: Kopec, J]]
[[Category: Oppermann, U]]
[[Category: Oppermann, U]]
[[Category: Kopec, J]]
[[Category: Von Delft, F]]
[[Category: Johansson, C]]
[[Category: Edwards, A]]
[[Category: Srikannathasan, V]]
[[Category: Srikannathasan, V]]
[[Category: Tobias, K]]
[[Category: Oxidoreductase]]
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