4uf3: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Deerpox virus DPV022 in complex with Bim BH3==

~~The entry~~ 4uf3 is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4uf3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UF3 FirstGlance]. <br>

~~Authors~~: ~~Burton~~, D.R., ~~Kvansakul~~, M.

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uf1|4uf1]], [[4uf2|4uf2]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uf3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uf3 RCSB], [http://www.ebi.ac.uk/pdbsum/4uf3 PDBsum]</span></td></tr>

~~Description: Deerpox virus DPV022 in complex with Bim BH3~~

</table>

[[~~Category~~: ~~Unreleased Structures~~]]

== Function ==

[[Category: Burton, D.R]]

[[http://www.uniprot.org/uniprot/B2L11_HUMAN B2L11_HUMAN]] Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.<ref>PMID:9430630</ref> <ref>PMID:11734221</ref> <ref>PMID:12019181</ref> <ref>PMID:11997495</ref> <ref>PMID:15147734</ref> <ref>PMID:15486195</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Burton, D R]]

[[Category: Kvansakul, M]]

[[Category: Apoptosis]]

[[Category: Bcl-2]]

[[Category: Bim bh3]]

[[Category: Deerpox virus]]

[[Category: Dpv022]]

[[Category: Viral protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Deerpox virus DPV022 in complex with Bim BH3==
+<StructureSection load='4uf3' size='340' side='right' caption='[[4uf3]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-The entry 4uf3 is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4uf3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UF3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UF3 FirstGlance]. <br>
-Authors: Burton, D.R., Kvansakul, M.
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uf1|4uf1]], [[4uf2|4uf2]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uf3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uf3 RCSB], [http://www.ebi.ac.uk/pdbsum/4uf3 PDBsum]</span></td></tr>
-Description: Deerpox virus DPV022 in complex with Bim BH3
+</table>
-[[Category: Unreleased Structures]]
+== Function ==
-[[Category: Burton, D.R]]
+[[http://www.uniprot.org/uniprot/B2L11_HUMAN B2L11_HUMAN]] Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis.<ref>PMID:9430630</ref> <ref>PMID:11734221</ref> <ref>PMID:12019181</ref> <ref>PMID:11997495</ref> <ref>PMID:15147734</ref> <ref>PMID:15486195</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Burton, D R]]
 [[Category: Kvansakul, M]]
+[[Category: Apoptosis]]
+[[Category: Bcl-2]]
+[[Category: Bim bh3]]
+[[Category: Deerpox virus]]
+[[Category: Dpv022]]
+[[Category: Viral protein]]