4bcf: Difference between revisions

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==Structure of CDK9 in complex with cyclin T and a 2-amino-4-heteroaryl- pyrimidine inhibitor==
==Structure of CDK9 in complex with cyclin T and a 2-amino-4-heteroaryl- pyrimidine inhibitor==
<StructureSection load='4bcf' size='340' side='right' caption='[[4bcf]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
<StructureSection load='4bcf' size='340' side='right' caption='[[4bcf]], [[Resolution|resolution]] 3.01&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4bcf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BCF FirstGlance]. <br>
<table><tr><td colspan='2'>[[4bcf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BCF FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T6Q:2-[[3-(4-ETHANOYL-1,4-DIAZEPAN-1-YL)PHENYL]AMINO]-4-[4-METHYL-2-(METHYLAMINO)-1,3-THIAZOL-5-YL]PYRIMIDINE-5-CARBONITRILE'>T6Q</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T6Q:2-[[3-(4-ETHANOYL-1,4-DIAZEPAN-1-YL)PHENYL]AMINO]-4-[4-METHYL-2-(METHYLAMINO)-1,3-THIAZOL-5-YL]PYRIMIDINE-5-CARBONITRILE'>T6Q</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pf6|1pf6]], [[4bcg|4bcg]], [[4bch|4bch]], [[4bci|4bci]], [[4bcj|4bcj]], [[4bck|4bck]], [[4bcm|4bcm]], [[4bcn|4bcn]], [[4bco|4bco]], [[4bcp|4bcp]], [[4bcq|4bcq]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pf6|1pf6]], [[4bcg|4bcg]], [[4bch|4bch]], [[4bci|4bci]], [[4bcj|4bcj]], [[4bck|4bck]], [[4bcm|4bcm]], [[4bcn|4bcn]], [[4bco|4bco]], [[4bcp|4bcp]], [[4bcq|4bcq]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bcf RCSB], [http://www.ebi.ac.uk/pdbsum/4bcf PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bcf OCA], [http://pdbe.org/4bcf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bcf RCSB], [http://www.ebi.ac.uk/pdbsum/4bcf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bcf ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4bcf" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Baumli, S]]
[[Category: Baumli, S]]
[[Category: Endicott, J A]]
[[Category: Endicott, J A]]
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