2iby: Difference between revisions

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|PDB= 2iby |SIZE=350|CAPTION= <scene name='initialview01'>2iby</scene>, resolution 1.85&Aring;
|PDB= 2iby |SIZE=350|CAPTION= <scene name='initialview01'>2iby</scene>, resolution 1.85&Aring;
|SITE=  
|SITE=  
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Acetyl-CoA_C-acetyltransferase Acetyl-CoA C-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.9 2.3.1.9]  
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetyl-CoA_C-acetyltransferase Acetyl-CoA C-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.9 2.3.1.9] </span>
|GENE= ACAT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|GENE= ACAT1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
|DOMAIN=
|RELATEDENTRY=[[2ib7|2IB7]], [[2ib8|2IB8]], [[2ib9|2IB9]], [[2ibu|2IBU]], [[2ibw|2IBW]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2iby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2iby OCA], [http://www.ebi.ac.uk/pdbsum/2iby PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2iby RCSB]</span>
}}
}}


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==Disease==
==Disease==
Known diseases associated with this structure: Alpha-methylacetoacetic aciduria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607809 607809]], Hypermethioninemia, persistent, autosomal dominant, due to methionine adenosyltransferase I/III deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=250850 250850]], Methionine adenosyltransferase deficiency, autosomal recessive OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=250850 250850]]
Known disease associated with this structure: Alpha-methylacetoacetic aciduria OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=607809 607809]]


==About this Structure==
==About this Structure==
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[[Category: Haapalainen, A M.]]
[[Category: Haapalainen, A M.]]
[[Category: Wierenga, R K.]]
[[Category: Wierenga, R K.]]
[[Category: CL]]
[[Category: COA]]
[[Category: GOL]]
[[Category: K]]
[[Category: MES]]
[[Category: alpha-beta-alpha-beta-alpha layered structure]]
[[Category: alpha-beta-alpha-beta-alpha layered structure]]
[[Category: beta-alpha-beta-alpha-beta-alpha-beta-beta topology]]
[[Category: beta-alpha-beta-alpha-beta-alpha-beta-beta topology]]
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[[Category: thiolase fold]]
[[Category: thiolase fold]]


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