Sandbox Reserved 969: Difference between revisions

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== '''Active Site & Ions Passage''' ==
== '''Active Site & Ions Passage''' ==


There are '''4 ions binding sites''' in the NaK channel <ref> PMID: 16467789</ref>. This diversity allows by different mechanisms to conduit <scene name='60/604488/Ion_binding_sites/1'>several cations</scene>. They have similar chemical environments but they have '''different ion selectivity'''. Two of them (sites S3 and S4) are conserved, that is to say they are the same than in the high selective K+ channel while S1 and S2 become a vestibular structure where K+ and Na+ ions can diffuse<ref> PMID: 19098915 </ref> .[[Image:biding_sites_lola.jpg|center|00px|The different ions binding site]]
There are '''4 ions binding sites''' in the NaK channel <ref> PMID: 16467789</ref>. This diversity allows by different mechanisms to conduit <scene name='60/604488/Ion_binding_sites/1'>several cations</scene>. They have similar chemical environments but they have '''different ion selectivity'''. Two of them (sites S3 and S4) are conserved, that is to say they are the same than in the high selective K+ channel while S1 and S2 become a vestibular structure where K+ and Na+ ions can diffuse<ref> PMID: 19098915 </ref> .[[Image:biding_sites_lola.jpg|center|thumbnail|400px|'''The different ions binding sites''']]


We will see for every binding site how his structure allows the passage of one or several ions.
We will see for every binding site how his structure allows the passage of one or several ions.