Sandbox Reserved 963: Difference between revisions
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====Interactions with His6==== | ====Interactions with His6==== | ||
His6 contacts both heavy- and light-chain elements with 10 side chain-side chain hydrophobic contacts with Asn100(E)H. Van der Waals contacts have been detected between His6 and <scene name='60/604482/My_first_scene/18'>Tyr32L</scene> of WO2. | His6 contacts both heavy- and light-chain elements with 10 side chain-side chain hydrophobic contacts with <scene name='60/604482/Asn100h/1'>Asn100(E)H</scene>. Van der Waals contacts have been detected between His6 and <scene name='60/604482/My_first_scene/18'>Tyr32L</scene> of WO2. | ||
With Phe4 and Arg5, His6 represents the core of the epitope of Aβ which sits at the heavy-chain/light-chain junction of the CDRs of WO2. | With Phe4 and Arg5, His6 represents the core of the epitope of Aβ which sits at the heavy-chain/light-chain junction of the CDRs of WO2. | ||
