Sandbox Reserved 967: Difference between revisions
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=== A heteromeric complex === | === A heteromeric complex === | ||
It has been shown that the Mammalian RNase complex is a heteromeric complex formed by 3 distinct proteins: <scene name='60/604486/H2a/1'>H2A</scene>,<scene name='60/604486/ | It has been shown that the Mammalian RNase complex is a heteromeric complex formed by 3 distinct proteins: <scene name='60/604486/H2a/1'>H2A</scene>,<scene name='60/604486/H2b/1'>H2B</scene> and <scene name='60/604486/H2c/1'>H2C</scene>. H2A protein is the catalytic subunit and H2B/H2C proteins are auxiliary subunits: they are structural domains that facilitate cohesion of the complex. | ||
The first domain structure of the complex, H2A, contains 301 amino acids, almost as H2B protein which computes 308 amino acids. H2C protein is the smallest subunit: it only has 166 amino acids. | The first domain structure of the complex, H2A, contains 301 amino acids, almost as H2B protein which computes 308 amino acids. H2C protein is the smallest subunit: it only has 166 amino acids. | ||
Each of these proteins adopts various secondary structures with β-strands and α-helices: | Each of these proteins adopts various secondary structures with β-strands and α-helices: | ||